The assistance package includes 495 oxygen concentrators – which extract oxygen from the air to give to patients – as well as ventilators.
India is seeing thousands of deaths a day amid oxygen shortages.
Prime Minister Boris Johnson said: “We stand side by side with India.”
The first shipment of equipment will leave the UK on Sunday and is due to arrive in the Indian capital, New Delhi, in the early hours of Tuesday morning.
In total, the UK will send nine airline containers of supplies this week, including 495 oxygen concentrators, 120 non-invasive ventilators and 20 manual ventilators.